Gel-form topical antibiotic compositions

A - Human Necessities – 61 – K

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A61K 47/00 (2006.01) A61K 9/06 (2006.01) A61K 9/10 (2006.01) A61K 31/315 (2006.01) A61K 31/70 (2006.01) A61K 33/30 (2006.01) C07H 15/16 (2006.01)

Patent

CA 1250236

GEL-FORM TOPICAL ANTIBIOTIC COMPOSITIONS ABSTRACT Topical pharmaceutical compositions, containing clindamycin phosphate, a zinc fatty acid salt, such as zinc acetate, and a non-aqueous vehicle, are disclosed. The compositions provide antibiotic performance and are present as physically stable, aesthetically-pleasing, clear, ringing gels, without requiring the use of con- ventional gelling agents. The method of topically treat- ing clindamycin responsive dermatoses, such as acne, using these compositions is also disclosed.

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