C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 11/08 (2006.01) C12Q 1/02 (2006.01) G01N 33/58 (2006.01)
Patent
CA 2717070
A gel microdrop composition is provided. In certain embodiments, the gel microdrop composition contains a polymer matrix, an effector particle that releases an effector molecule into the polymer matrix, a first reporter particle that emits a first optically detectable signal and a second reporter particle that emits a second optically detectable signal that is distinguishable from the first optically de-tectable signal, where the effector particle and said first and second reporter parti-cles are encapsulated by the polymer matrix. Methods of screening that employ the gel microdrop composition and methods of making the gel microdrop composition are also disclosed.
La présente invention concerne une composition de microgouttes de gel. Dans certains modes de réalisation, la composition de microgouttes de gel contient une matrice polymère, une particule effectrice qui libère une molécule effectrice dans la matrice polymère, une première particule rapporteuse qui émet un premier signal optiquement détectable et une seconde particule rapporteuse qui émet un second signal optiquement détectable qui se distingue du premier signal optiquement détectable, la particule effectrice et lesdites première et seconde particules rapporteuses étant encapsulées dans la matrice polymère. Linvention concerne également des procédés de criblage qui utilisent la composition de microgouttes de gel et des procédés de fabrication de la composition de microgouttes de gel.
Crystal Bioscience Inc.
Fetherstonhaugh & Co.
LandOfFree
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