Gel preparation containing polystyrene-sulfonates

Details Gel preparation containing polystyrene-sulfonates Gel preparation containing polystyrene-sulfonates

A - Human Necessities

61

K

A61K 9/06 (2006.01) A61K 9/00 (2006.01) A61K 31/795 (2006.01)

Patent

CA 2306005

The invention relates to a polystyrene sulfonate- containing gel preparation for therapy of hyperpotassemia, wherein the particle size of polystyrene sulfonate is controlled within the range of at least 5 - 100µm, the viscosity of its solution before gelation is adjusted depending on the particle size by adding a thickening agent, and the polystyrene sulfonate particles after gelation is uniformly dispersed therein. More preferably, a water-displacing agent is contained, whereby the amount of water in the preparation is reduced. This gel preparation does not cause a sense of foreign matter or a sense of roughness in the oral cavity upon ingestion and intake, thus making it unnecessary to drink water for ingestion, and further its water content is low, so that control of water intake is made easy, even in the case of a patient with renal insufficiency who is subjecting to restriction in intake of water to significant improve the quality of life of the patient.

Préparation de gel contenant un sulfonate de polystyrène et permettant de traiter l'hyperkaliémie. On régule la granulométrie dudit sulfonate de polystyrène à l'intérieur d'une plage d'au moins 5 à 100 mu m et on contrôle sa viscosité avant gélification en ajoutant un épaississant, de façon à obtenir une dispersion homogène des grains de sulfonate de polystyrène. De préférence, la préparation contient des agents pouvant remplacer l'eau, ce qui diminue sa teneur en humidité. Comme la préparation de gel ne présente ni goût ni rugosité désagréable dus à ses principes actifs lorsqu'on l'introduit dans la cavité buccale, on peut la prendre sans eau. De plus, elle a une faible teneur en humidité, ce qui permet de surveiller facilement l'absorption d'eau même dans le cas de patients chez lesquels l'absorption d'eau doit être surveillée de près, tels que ceux atteints d'insuffisance rénale, et donc améliore considérablement leur qualité de vie.

Affiliated with

Also associated with

Rating

Gel preparation containing polystyrene-sulfonates does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Gel preparation containing polystyrene-sulfonates, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Gel preparation containing polystyrene-sulfonates will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1835698