Gel-shell beads with adsorbed or bound biomolecules

Details Gel-shell beads with adsorbed or bound biomolecules Gel-shell beads with adsorbed or bound biomolecules

G - Physics

01

N

G01N 33/543 (2006.01) C07K 1/04 (2006.01) C07K 1/22 (2006.01) C40B 30/04 (2006.01) G01N 1/34 (2006.01)

Patent

CA 2544262

Disclosed are gel-coated beads (including HydrogelTM -coated beads), which are capable of adsorbing, or absorbing, proteins and other biomolecules onto or into the gel coating. The gel~coated beads with absorbed or adsorbed biomolecules are suitable for use in an assays, purification or other purposes. The beads have a core made from any of a number of materials, including latex, coated with the gel shell. The biomolecules can be retained within the gel, following adsorption, by covalent attachment, or, by selection of conditions of ambient pH and/or ionic strength such that they are retained without further reaction. Therefore, adsorbed proteins would retain the ability to bind to their respective ligands.

L'invention concerne des billes revêtues de gel, notamment des billes revêtues d'hydrogel, qui sont capables d'adsorber ou d'absorber des protéines et d'autres biomolécules sur ou dans le revêtement de gel. Les billes revêtues de gel à biomolécules absorbées ou adsorbées selon l'invention peuvent être utilisées dans des dosages biologiques, pour la purification ou à d'autres fins. Ces billes ont une âme constituée d'un matériau parmi un certain nombre de matériaux, latex compris, et revêtue d'une coque en gel. Les biomolécules peuvent être retenues à l'intérieur du gel, après adsorption, par fixation covalente ou par sélection de conditions de pH ambiant et/ou de force ionique telles que les biomolécules sont retenues sans autre réaction. Ainsi, les protéines adsorbées conservent leur capacité à se lier à leurs ligands respectifs.

Affiliated with

Also associated with

Rating

Gel-shell beads with adsorbed or bound biomolecules does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Gel-shell beads with adsorbed or bound biomolecules, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Gel-shell beads with adsorbed or bound biomolecules will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1364671