Gelatin capsule fill able to foam

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/48 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2174777

A pharmaceutical product for the treatment of reflux or oesophagitis, gastritis or peptic ulceration in the form of a chewable soft gelatine capsule with a fill comprising (a) polymeric material selected from alginic acid, alginates, pectin, xanthan, gellan, carageenan and mixtures thereof, (b) a carbonate or bicarbonate salt; (c) an oil-based or hydrophilic based liquid vehicle; wherein on oral ingestion by a patient the gelatine capsule shell ruptures and the fill reacts with the acid contents of the stomach to produce a carbonated floating gelatinous raft of specified rigidity.

Produit pharmaceutique pour le traitement du reflux gastro-oesophagien, de la gastrite ou de l'ulcère gastro-duodénal, se présentant sous la forme d'une gélule de gélatine souple que l'on peut mastiquer, l'intérieur de cette gélule comprenant: (a) un matériau polymère choisi parmi un acide alginique, des alginates, une pectine, du xanthane, du gellane, de la carraghénane et des mélanges de ces substances; (b) un sel carbonaté ou bicarbonaté; (c) un véhicule liquide à base d'huile ou à base hydrophile; l'ingestion orale de cette gélule par un patient provoque la rupture de l'enveloppe gélatineuse de la gélule et les substances contenues peuvent réagir avec les substances acides contenues dans l'estomac afin de produire une barrière gélatineuse carbonée flottante de consistance spécifiée.

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