Geldanamycin derivative and use of same to treat cancer

Details Geldanamycin derivative and use of same to treat cancer Geldanamycin derivative and use of same to treat cancer

C - Chemistry, Metallurgy

07

D

C07D 225/06 (2006.01) A61K 31/395 (2006.01)

Patent

CA 2430692

A geldanamycin derivative exhibiting significant preliminary in vivo activity, particularly significant oral in vivo activity, and a method of treating or preventing cancer in a host comprising administrering a geldanamycin derivative to a host in an amount sufficient to treat or prevent cancer.

L'invention concerne un dérivé de geldanamycine ayant une activité préliminaire <i>in vivo</i> considérable, notamment une activité orale <i>in vivo </i>considérable, et un procédé de traitement ou de prévention du cancer dans un hôte, qui consiste à administrer un dérivé de geldanamycine à un hôte, en dose suffisante pour le traitement ou la prévention du cancer.

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