Gelled composite

C - Chemistry – Metallurgy – 08 – J

Patent

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Details

C08J 9/42 (2006.01) C12N 5/071 (2010.01) A61K 31/715 (2006.01) A61K 47/36 (2006.01) A61L 15/22 (2006.01) A61L 27/38 (2006.01) A61L 27/48 (2006.01) A61L 27/56 (2006.01) A61P 41/00 (2006.01) C08J 3/075 (2006.01) C08L 5/04 (2006.01) C12N 5/00 (2006.01) C12N 11/02 (2006.01)

Patent

CA 2643084

The invention relates to composites comprising a polysaccharide gelled within pores of a foam, methods of preparation, and uses thereof, for example, in biomedical applications such as cell culture media and implants, controlled release delivery systems, food applications, industrial applications, and personal care applications such as cosmetic and oral hygiene. The composites of the present invention are simple to formulate using few steps and are useful for entrapping heat-sensitive components, such as cells, drugs, flavors or fragrances within the polysaccharide gel. In addition, the invention provides for a composite able to gently immobilize fragile components, such as living cells, without exposing such components to shear forces.

L'invention concerne des composites comprenant un polysaccharide gélifié à l'intérieur des pores d'une mousse, des procédés de préparation et des utilisations de ceux-ci, par exemple dans des applications biomédicales telles que des milieux de culture de cellules et des implants, des systèmes d'administration à libération contrôlée, des applications alimentaires, des applications industrielles et des applications de soins personnels telles que la cosmétique et l'hygiène orale. Les composites de la présente invention sont simples à formuler en utilisant un petit nombre d'étapes et sont utiles pour piéger des composants thermosensibles, tels que des cellules, des médicaments, des arômes et des parfums à l'intérieur du gel de polysaccharide. En plus, l'invention concerne un composite permettant d'immobiliser en douceur des composants fragiles, tels que des cellules vivantes, sans exposer de tels composants à des forces de cisaillement.

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