C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 11/02 (2006.01) A61K 9/16 (2006.01) A61K 9/50 (2006.01) A61K 9/66 (2006.01) A61K 35/12 (2006.01) A61K 38/42 (2006.01) A61K 38/44 (2006.01) A61K 47/30 (2006.01) A61L 17/00 (2006.01) A61L 24/00 (2006.01) A61L 24/04 (2006.01) A61L 26/00 (2006.01) A61L 27/00 (2006.01) A61L 27/34 (2006.01) A61L 27/38 (2006.01) A61L 27/52 (2006.01) A61L 29/08 (2006.01) A61L 31/14 (2006.01) C07K 17/02 (2006.01) C08F 290/00 (2006.01) C08F 290/02 (2006.01) C08F 290/06 (2006.01) C08F 291/00 (2006.01) C09D 153/00 (2006.01) C12N 5
Patent
CA 2117584
Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions to encapsulate tissues, cells, or biologically active materials. The polymeric materials are particularly useful as tissue adhesives, coatings for tissue lumens including blood vessels, coatings for cells such as islets of Langerhans, coatings, plugs, supports or substrates for contact with biological materials such as the body, and as drug delivery devices for biologically active molecules.
Des macromères hydrosolubles sont modifiés par l'addition de groupes de radicaux libres polymérisables, tels que ceux contenant une liaison carbone-carbone double ou triple , qui peuvent être polymérisés dans des conditions douces pour encapsuler des tissus, des cellules ou du matériel bioactif. Les polymères sont particulièrement utiles comme adhésifs tissulaires, revêtements pour lumières tissulaires, dont les vaisseaux sanguins, revêtements pour cellules, comme les ilôts de Langerhans, des revêtements, des bouchons, des supports ou des substrats entrant en contact avec des matières biologiques comme le corps et en tant que dispositif d'administration de molécules bioactives.
Desai Neil P.
Hill-West Jennifer L. (nee Hill)
Hossainy Syed F.
Hubbell Jeffrey A.
Pathak Chandrashekhar P.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Board Of Regents The University Of Texas System
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