Gemfibrozil containing pharmaceutical compositions

Details Gemfibrozil containing pharmaceutical compositions Gemfibrozil containing pharmaceutical compositions

A - Human Necessities

61

K

A61K 31/19 (2006.01) A61K 9/20 (2006.01) A61K 31/192 (2006.01) A61K 47/20 (2006.01)

Patent

CA 2149282

The invention relates to oral solid pharmaceutical composition containing as active ingredient gemfibrozil and conventional pharmaceutical auxiliary agents comprising as surfactant bis-(2-ethyl-hexyl)-sodium- sulfosuccinate in an amount of 0.05-0.5 % by weight related to the gemfibrozil content of the composition. The pharmaceutical compositions according to the present invention contain a relatively small amount of a surfactant, provide uniform dissolution of the active ingredient among the different batches and the standard deviation of the dissolution rate is low.

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