Geminal carboxylic acids and esters thereof, pharmaceutical...

C - Chemistry – Metallurgy – 07 – C

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C07C 271/22 (2006.01) A61K 31/225 (2006.01) A61K 31/27 (2006.01) A61K 31/33 (2006.01) C07C 69/708 (2006.01) C07C 69/712 (2006.01) C07C 229/24 (2006.01) C07C 323/44 (2006.01) C07C 335/32 (2006.01) C07D 207/16 (2006.01) C07D 211/34 (2006.01) C07D 211/42 (2006.01) C07D 211/46 (2006.01) C07D 213/32 (2006.01) C07D 213/55 (2006.01) C07D 213/65 (2006.01) C07D 213/68 (2006.01) C07D 233/42 (2006.01) C07D 239/10 (2006.01) C07D 261/08 (2006.01) C07D 295/15 (2006.01) C07D 307/46 (2006.01) C07D 307/54 (2006.01) C07D 309

Patent

CA 2198525

Compounds of formula I: (see fig. I) wherein Ra, Rb, .PHI., B and R are as defined in the disclosure, have antagonistic activity on osteoclast hyper-reactivity.

es composés de formule I : (voir fig. I) où Ra, Rb, .PHI., B et R sont définis dans l'exposé de l'invention, ont une activité antagoniste à l'égard de l'hyper-réactivité des ostéoclastes.

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