Geminal dihalogen derivatives of condensed pyrimidine-4-one...

Details Geminal dihalogen derivatives of condensed pyrimidine-4-one... Geminal dihalogen derivatives of condensed pyrimidine-4-one...

C - Chemistry, Metallurgy

07

D

260/242.01, 260/

C07D 471/04 (2006.01) C07D 487/04 (2006.01) C09B 62/00 (2006.01)

Patent

CA 1141379

ABSTRACT Geminal dihalogen derivatives of condensed pyrimidine-4-one compounds of the general formula Image I [wherein R represents hydrogen, lower alkyl, or lower alkoxycarbony; R1 represents hydrogen, lower alkyl, carboxy, ester group or a derivative thereof, cyano, phenyl or halogen; R2 represents hydrogen, lower alkyl or phenyl; X represents halogen; n is the integer 0, 1 or 2] and the salts and optically active antipodes thereof. The compounds I are valuable intermediates in the synthesis of compounds having antiallergic or antiasthmatic activity and some of the compounds I themselves posses pharmacological activity.

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