Gender-specific separation of sperm cells and embryos

Details Gender-specific separation of sperm cells and embryos Gender-specific separation of sperm cells and embryos

C - Chemistry, Metallurgy

12

N

C12N 5/076 (2010.01) C12Q 1/68 (2006.01) A01K 67/02 (2006.01)

Patent

CA 2708751

Disclosed are sperm cells or embryos comprising a labeled oligonucleotide bound to a gender-specific repeat sequence. Methods for separating sperm cells or embryos containing a labeled oligonucleotide from sperm cells not containing the labeled oligonucleotide produce gender-enriched sperm cell fractions. The separated fractions are useful in producing offspring of a predetermined sex.

L'invention concerne des spermatozoïdes et des embryons qui comprennent un oligonucléotide marqué lié à une séquence répétitive spécifique à chaque sexe. Des procédés marque des séparation de spermatozoïdes ou d'embryons contenant un oligonucléotide marqué des spermatozoïdes ne contenant pas un oligonucléotide marqué produisent des fractions de sperme enrichies de spermatozoïdes du sexe désiré. Les fractions séparées sont utiles pour la production d'une progéniture d'un sexe prédéterminé.

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