C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) C07K 14/47 (2006.01) C07K 14/61 (2006.01) C12N 5/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2339518
The invention describes a previously unknown gene, termed 5'OT-EST, which is responsible for inducing an obesity and/or infertility phenotype in transgenic animals, and transgenic animals comprising mutants of 5'OT-EST which are useful for assaying compounds for the treatment of obesity and/or infertility.
L'invention concerne un gène jusqu'ici inconnu, dénommé 5'OT-EST et qui est responsable de l'apparition d'un phénotype d'obésité et/ou d'infertilité chez des animaux transgéniques; ainsi que des animaux transgéniques, y compris des mutants de 5'OT-EST s'utilisant dans le dosage biologique de composés destinés au traitement de l'obésité et/ou de l'infertilité.
Flavell David
Le Tissier Paul
Robinson Iain Clive Andrew Franklin
Stoye Jonathan Paul
Wells Sara Elizabeth
Mbm Intellectual Property Law Llp
Medical Research Council
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