C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C12N 9/20 (2006.01) C12N 15/12 (2006.01) C12Q 1/02 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2291484
The present invention relates to a novel transcription factor, called FREAC 11, which is a member of the forkhead family of transcription factors. The invention also relates to the gene freac 11 encoding said transcription factor. FREAC 11 is expressed in adipose tissue and regulates adipose tissue expressed genes involved in lipid metabolism and adipocyte differentiation. Furthermore, the invention relates to drug and drug target applications of FREAC 11 and freac 11, respectively.
La présente invention concerne un nouveau facteur de transcription, appelé FREAC 11, qui appartient à la famille des facteurs de transcription en tête de fourche. L'invention concerne également le gène freac 11 codant ce facteur de transcription. Le FREAC 11, exprimé dans des tissus adipeux, régule les gènes qui sont exprimés dans les tissus adipeux et sont impliqués dans le métabolisme des lipides et la différenciation adipocyte. En outre, l'invention concerne un médicament et des applications de ciblage de médicaments respectivement du FREAC 11 et du freac 11.
Carlsson Peter
Enerback Sven
Gowling Lafleur Henderson Llp
Leangene Ab
Pharmacia & Upjohn Ab
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