Gene associated with bone disorders

Details Gene associated with bone disorders Gene associated with bone disorders

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A01K 67/00 (2006.01) A61P 19/10 (2006.01) C07K 1/00 (2006.01) C07K 14/47 (2006.01) C07K 14/51 (2006.01) C07K 16/18 (2006.01) C07K 16/22 (2006.01) C12N 1/20 (2006.01) C12N 15/63 (2006.01) C12P 21/02 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2456199

The present invention relates to identifying genes that are differentially regulated or expressed in bone deposition disorders. Specifically, a novel gene has been identified as being differentially regulated during the maturation of osteoblasts and whose expression can be correlated, for example, with bone deposition disorders such as osteoporosis (including correlation with degrees of severity of the disease).

L'invention concerne l'identification de gènes qui sont régulés ou exprimés de façon différentielle dans des troubles du dépôt osseux. Plus spécifiquement, l'invention concerne un nouveau gène identifié, à régulation différentielle durant la maturation des ostéoblastes, et dont l'expression peut être corrélée, par exemple, avec des troubles du dépôt osseux tels que l'ostéoporose (notamment corrélé avec des degrés de gravité de la maladie).

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