Gene coding for erbin, and diagnostic and therapeutic uses...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 15/11 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2405124

The invention concerns a novel gene, coding for a protein named Erbin (Erbb2 Interacting protein), which interacts with the intracellular part of ERBB2/HER-2 receptors, involved in particular in the development of cancers, the diagnostic and therapeutic uses of novel nucleotide sequences and identified amino acids.

Cette invention concerne un nouveau gène, qui code pour une protéine désignée Erbin (pour "Erbb2 Interacting protein"), qui interagit avec la partie intracellulaire des récepteurs ERBB2/HER-2, impliquée notamment dans le développement des cancers, les utilisations diagnostiques et thérapeutiques des nouvelles séquences nucléotidiques et d'acides aminés identifiées.

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