Gene coding for modified bone morphogenic protein receptor

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/62 (2006.01) A61K 38/18 (2006.01) C07K 14/51 (2006.01) C07K 14/71 (2006.01) C07K 19/00 (2006.01) C12N 15/18 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2191321

This invention relates to the gene coding the modified bone- morphogenetic-protein (BMP) receptor, to the modified BMP receptor expressed by said gene, and to application of said modified BMP receptor. Since said modified BMP receptor of the present invention specifically binds BMP, said receptor may be useful for purification of BMP, as a reagent for diagnosing various diseases associated with BMP, as a reagent for research, and as a medicine, etc.

La présente invention concerne le codage génique pour un récepteur modifié de la protéine morphogénétique osseuse (BMP), une modification du récepteur de la BMP exprimé au moyen du gène et l'utilisation du récepteur modifié. Etant donné que le récepteur modifié de la BMP lie spécifiquement la BMP, il peut être largement utilisé notamment comme réactif de purification de la BMP, comme réactif de diagnostic de différentes affections relatives à la BMP, comme réactif d'étude et comme médicament.

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