A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/127 (2006.01) C12N 15/63 (2006.01) C12N 15/88 (2006.01)
Patent
CA 2546616
A liposome composition and method for delivery of a nucleic acid in vivo or ex vivo is described. The liposomes in the composition are comprised of (i) a cationic lipid and (ii) a lipid joined to a hydrophilic polymer by a releasable linkage. The liposomes are associated with a nucleic acid for delivery to a cell.
La présente invention a trait à une composition de liposomes et un procédé d'administration d'un acide nucléique in vivo ou ex vivo. Les liposomes de la composition comportent (i) un lipide cationique et (ii) un lipide assemblé à un polymère hydrophile par une liaison amovible. Les liposomes sont associés à un acide nucléique pour l'administration à une cellule.
Huang Shi-Kun
Zalipsky Samuel
Alza Corporation
Gowling Lafleur Henderson Llp
LandOfFree
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