Gene expression control

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/11 (2006.01) A61K 31/70 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2180032

The present invention relates to new vectors, pharmaceutical compositions containing them, and their therapeutical uses. More particularly, it relates to double strand DNA molecules coding for an RNA forming a triple helix with a single strand target nucleic acid. Said molecules act very selectively and efficiently on the expression of genes.

La présente invention concerne de nouveaux vecteurs, les compositions pharmaceutiques les contenant, et leurs utilisations thérapeutiques. Plus partic- ulièrement, elle concerne des molécules d'ADN double-brin codant pour un ARN formant une triple hélice avec un acide nucléique-cible simple-brin. Ces molécules agissent de manière très sélective et efficace sur l'expression de gènes.

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