Gene expression in biological conditions

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) A61K 38/00 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C40B 30/04 (2006.01)

Patent

CA 2414621

The present invention relates to a metod of determining the presence or absence of a biological condition in animal tissue, wherein the expression of genes in normal tissue and tissue from the biological condition is examined and correlated to standards. The invetion further relates to the treatment of the biological condition and an assay for determining the condition. More particularly the invention concerns gene expression in epithelial tissue,such as urianry bladder under both normal and abnormal conditions.

L'invention concerne un procédé permettant de déterminer la présence ou l'absence d'un état biologique dans des tissus animaux, l'expression des gènes dans des tissus normaux et des tissus issus de l'état biologique étant examinée et mise en corrélation avec des normes. L'invention concerne également le traitement de l'état biologique et un dosage permettant de déterminer l'état. Plus précisément, l'invention concerne une expression génique dans des tissus épithéliaux, tels qu'une vessie urinaire, dans des conditions normales et anormales.

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