Gene expression markers for response to egfr inhibitor drugs

Details Gene expression markers for response to egfr inhibitor drugs Gene expression markers for response to egfr inhibitor drugs

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2527321

The present invention concerns prognostic markers associated with cancer. In particular, the invention concerns prognostic methods based on the molecular characterization of gene expression in paraffin-embedded, fixed samples of cancer tissue, which allow a physician to predict whether a patient is likely to respond well to treatment with an EGFR inhibitor.

L'invention concerne des marqueurs prédictifs associés au cancer. Plus précisément, l'invention concerne des procédés prédictifs fondés sur la caractérisation moléculaire de l'expression génique dans des échantillons de tissus cancéreux fixes, noyés dans une paraffine, qui permettent au médecin de prévoir si le patient est susceptible de bien réagir au traitement avec un inhibiteur de EGFR.

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