Gene expression monitoring using universal arrays

Details Gene expression monitoring using universal arrays Gene expression monitoring using universal arrays

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 19/10 (2006.01) C07H 19/20 (2006.01) C07H 21/00 (2006.01) C12N 15/10 (2006.01) C12P 19/34 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) C12N 15/09 (2006.01)

Patent

CA 2358831

Methods are provided for monitoring a large number of genes using cipher probes. In preferred embodiments, the cipher probes are immobilized on a substrate to form a universal array that is suitable for monitoring the expression of almost any genes. Mediator probes are used in some embodiments to hybridize with the cipher probes and nucleic acids derived from transcripts of genes.

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