A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 38/15 (2006.01)
Patent
CA 2317003
An expression potentiator or reactivation promoter of a transgene, which contains FR901228 of the formula (I) Image or a salt thereof as an active ingredient. FR901228 or a salt thereof used in the present invention as an active ingredient shows not only in vitro but in vivo superior potentiation of a expression of a transgene and promotion of the reactivation of the transgene. Therefore, it can be advantageously used in clinical situations, particularly for a gene therapy.
Kaneda Yasufumi
Nakajima Hidenori
Yamano Tomoki
Fujisawa Pharmaceutical Co. Ltd.
Kaneda Yasufumi
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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