Gene expression potentiator

A - Human Necessities – 61 – K

Patent

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Details

A61K 48/00 (2006.01) A61K 38/15 (2006.01)

Patent

CA 2317003

An expression potentiator or reactivation promoter of a transgene, which contains FR901228 of the formula (I) Image or a salt thereof as an active ingredient. FR901228 or a salt thereof used in the present invention as an active ingredient shows not only in vitro but in vivo superior potentiation of a expression of a transgene and promotion of the reactivation of the transgene. Therefore, it can be advantageously used in clinical situations, particularly for a gene therapy.

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