Gene expression profiles and methods of use

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2637369

The present invention relates to gene expression profiles, microarrays comprising nucleic acid sequences representing gene expression profiles, and methods of using expression profiles and microarrays. The invention also provides methods and compositions for diagnostic assays for detecting cancer and therapeutic methods and compositions for treating cancer. The invention also provides methods for designing, identifying, and optimizing therapeutics for cancer.

La présente invention concerne des profils d~expression génique, des microéchantillons comprenant des séquences d~acide nucléique qui représentent les profils d~expression génique et des procédés d~utilisation des profils d~expression et des microéchantillons. L~invention a également trait à des procédés et des compositions pour dosages diagnostiques de détection du cancer, ainsi que des procédés et des compositions thérapeutiques pour le traitement du cancer. Enfin, l~invention divulgue des procédés de conception, d~identification et d~optimisation de thérapies anticancéreuses.

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