Gene expression profiles and methods of use

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) C40B 40/06 (2006.01)

Patent

CA 2540894

The present invention relates to gene expression profiles for lung cancer, microarrays comprising nucleic acid sequences representing gene expression profiles, and methods of using expression profiles and microarrays. The invention also provides methods and compositions for diagnostic assays for detecting cancer and therapeutic methods and compositions for treating cancer. The invention also provides methods for designing, identifying, and optimizing therapeutics for cancer.

La présente invention concerne des profils d'expression génique destinés au cancer du poumon, des microréseaux contenant des séquences d'acides nucléiques représentant des profils d'expression génique, et des méthodes d'utilisation des profils d'expression et des microréseaux. Cette invention a aussi pour objet des méthodes et des compositions destinées aux dosages diagnostiques servant à déceler un cancer, ainsi que des méthodes et des compositions de traitement de cancer. Ladite invention a également trait à des méthodes de conception, d'identification et d'optimisation d'agents thérapeutiques pour le cancer.

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