Gene expression profiles being predictive for the response...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2604549

The present invention relates to a method for providing a gene expression profile being predictive for the specific response of an individual tumor to a pharmaceutically effective compound, the use thereof, a microarray wherein the nucleotide sequences attached to the substrate consist of nucleotide sequences corresponding to the predictive genes of said gene expression profile, and a diagnostic kit containing said microarray.

La présente invention concerne un procédé permettant d'obtenir un profil d'expression génétique prédictif de la réponse spécifique d'une tumeur individuelle à un composé pharmaceutiquement efficace, l'utilisation dudit profil, un microréseau dans lequel les séquences nucléotidiques fixées au substrat sont constituées de séquences nucléotidiques correspondant aux gènes prédictifs dudit profil d'expression génétique, ainsi qu'une trousse de diagnostic contenant ledit microréseau.

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