Gene expression profiling for identification, monitoring,...

Details Gene expression profiling for identification, monitoring,... Gene expression profiling for identification, monitoring,...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01)

Patent

CA 2680692

A method is provided in various embodiments for determining a profile data set for a subject with prostate cancer or conditions related to prostate cancer based on a sample from the subject, wherein the sample provides a source of RNAs. The method includes using amplification for measuring the amount of RNA corresponding to at least 1 constituent from Tables 1-4. The profile data set comprises the measure of each constituent, and amplification is performed under measurement conditions that are substantially repeatable.

L'invention concerne un procédé dans divers modes de réalisation pour déterminer un ensemble de données de profil pour un sujet avec un cancer de la prostate ou des états apparentés au cancer de prostate sur la base d'un échantillon provenant du sujet, l'échantillon fournissant une source d'ARN. Le procédé comprend l'utilisation de l'amplification pour la mesure de la quantité d'ARN correspondant à au moins 1 constituant des Tableaux 1-4. L'ensemble des données de profil comprend la mesure de chaque constituant, et une amplification est effectuée dans des conditions de mesure qui sont sensiblement aptes à être répétées.

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