Gene expression profiling for identification, monitoring and...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2668831

A method is provided in various embodiments for determining a profile data set for a subject with skin cancer or a condition related to skin cancer based on a sample from the subject, wherein the sample provides a source of RNAs. The method includes using amplification for measuring the amount of RNA corresponding to at least 1 constituent from Tables 1-6. The profile data set comprises the measure of each constituent, and amplification is performed under measurement conditions that are substantially repeatable.

L'invention concerne, dans plusieurs modes de réalisation, un procédé permettant de déterminer un ensemble de données de profil pour un sujet souffrant de cancer de la peau ou d'une condition en rapport avec le cancer de la peau sur la base d'un échantillon du sujet, où l'échantillon fournit une source d'ARN. Le procédé consiste à utiliser l'amplification aux fins de mesurer la quantité d'ARN correspondant à au moins un constituant des Tables 1-6. L'ensemble de données de profil comprend la mesure de chaque constituant et l'amplification est exécutée dans des conditions de mesure sensiblement répétables.

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