C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01)
Patent
CA 2624359
A method is provided in various embodiments for determining a profile data set for a subject with rheumatoid arthritis or inflammatory conditions related to rheumatoid arthritis based on a sample from the subject, wherein the sample provides a source of RNAs. The method includes using amplification for measuring the amount of RNA corresponding to at least 2 constituents from a gene panel. The profile data set comprises the measure of each constituent, and amplification is performed under measurement conditions that are substantially repeatable.
Divers modes de réalisation de l'invention concernent un procédé permettant de déterminer un ensemble de données de profil pour un sujet souffrant de polyarthrite rhumatoïde ou d'états inflammatoires relatifs à la polyarthrite rhumatoïde, en fonction d'un échantillon prélevé chez le sujet, l'échantillon fournissant une source d'ARN. Le procédé consiste à utiliser l'amplification aux fins de mesure de la quantité d'ARN correspondant à au moins deux constituants des Tables 1-2 et des Tables 4-10. L'ensemble de données de profil comprend la mesure de chaque constituant et l'amplification est exécutée dans des conditions de mesure sensiblement répétables.
Bankaitis-Davis Danute
Siconolfi Lisa
Storm Kathy
Trollinger David B.
Wassmann Karl
Ridout & Maybee Llp
Source Mdx
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