Gene expression profiling for identification of prognostic...

Details Gene expression profiling for identification of prognostic... Gene expression profiling for identification of prognostic...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G06F 19/20 (2011.01) C40B 30/02 (2006.01) G01N 33/48 (2006.01)

Patent

CA 2623403

mRNA transcript profiling can be used to formulate molecular predictors of distant metastasis for primary NPCs. The predicted results are highly correlated with short metastasis-free and overall survival. Predictions are made using 52-genes based and 12- genes based predictors.

Dans l'invention, un profilage de transcription d'ARNm peut être utilisé pour formuler des prédicteurs moléculaires de métastases distantes pour des carcinomes nasopharyngiens primaires (NPC). Les résultats prédits sont hautement corrélés avec une survie globale exempte de métastases. Des prédictions sont effectuées à l'aide de prédicteurs fondés sur des gènes 52 et sur des gènes 12.

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