Gene expression regulatory dna

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/77 (2006.01) C12N 1/21 (2006.01) C12N 9/10 (2006.01) C12N 9/38 (2006.01) C12N 9/88 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2077308

The present invention provides a gene expression regulatory DNA and a process for preparing a protein using the same. A DNA derived from the isocitrate lyase (ICL) gene of a coryneform bacterium regulates expression of a structural gene encoding a protein when incorporated into a vector DNA together with said structural gene and introduced into a host coryneform bacterium, and a useful protein can be efficiently produced using the DNA.

L'invention fournit un ADN de régulation de l'expression génique et un procédé de préparation d'une protéine à l'aide de l'ADN. Un ADN dérivé du gène de l'isocitrate lyase (ICL) d'une « bactérie coryneforme » régule l'expression d'un gène de structure codant pour une protéine lorsqu'il est incorporé dans un ADN vecteur avec le gène de structure en question et introduit dans une « bactérie coryneforme » hôte. Une protéine utile peut être efficacement produite à l'aide de l'ADN.

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