C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2737382
Methods of assessing genomic instability in breast cancer tissue by measuring the expression level of genes CD-KN2A, SCYA18, STK15, NXF1, cDNA Dkfzp762M127, p28 KIAA0882, MYB, Human clone 23948, RERG, HNF3A, and ACADSB or a nucleic acid sequence comprising about 90% or greater sequence identity to SEQ ID NO: 21 in breast cancer tissue, an array suitable for use in such methods, and related methods and compositions.
L'invention porte sur des procédés d'évaluation de l'instabilité génomique dans un tissu atteint de cancer du sein par la mesure du taux d'expression des gènes CDKN2A, SCYA18, STK15, NXFl, l'ADNc de Dkfzp762M127, p28 de KIAA0882, MYB, clone humain 23948, RERG, HNF3A, et ACADSB ou une séquence d'acide nucléique comprenant une identité de séquence d'environ 90 % ou plus par rapport à SEQ ID NO: 21 dans un tissu atteint de cancer du sein, un réseau approprié pour une utilisation dans de tels procédés, et sur des procédés et des compositions apparentés.
Auer Gert
Guo Nancy Lan
Habermann Jens
Reid Karl Thomas
Auer Gert
Departmen T. Of Health And Human Services The United States Of America As Represented By The Secretary
Ridout & Maybee Llp
West Virginia University Research Corporation
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