Gene involved in metabolic energy and obesity

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C07K 14/575 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2307839

The present invention relates generally to a nucleic acid molecule which encodes a protein associated with the modulation of obesity, diabetes and metabolic energy levels. More particularly, the present invention is directed to a nucleic acid molecule and a recombinant and purified naturally occurring protein encoded thereby and their use in therapeutic and diagnostic protocols for conditions such as obesity, diabetes and energy imbalance. The subject nucleic acid molecule and protein and their derivatives, homologues, analogues and mimetics are proposed as therapeutic and diagnostic agents for obesity, diabetes and energy imbalance.

De manière générale, l'invention concerne une molécule d'acide nucléique codant pour une protéine associée à la modulation de l'obésité, du diabète et du métabolisme énergétique. Plus particulièrement, elle concerne une molécule d'acide nucléique et une protéine naturelle recombinante et purifiée codée par ladite molécule, ainsi que leur utilisation dans des protocoles thérapeutiques et diagnostiques visant des pathologies telles que l'obésité, le diabète et les déséquilibres énergétiques. La molécule d'acide nucléique et la protéine de l'invention, ainsi que leurs dérivés, homologues, analogues et mimétiques, sont proposés comme agents thérapeutiques et diagnostiques pour l'obésité, le diabète et les déséquilibres énergétiques.

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