Gene knockout mesophilic and thermophilic organisms, and...

C - Chemistry – Metallurgy – 12 – N

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C12N 15/74 (2006.01) C12N 1/21 (2006.01) C12N 15/00 (2006.01) C12N 15/52 (2006.01) C12N 15/63 (2006.01) C12P 1/04 (2006.01) C12P 7/06 (2006.01) C12P 7/10 (2006.01)

Patent

CA 2685879

One aspect of the invention relates to a genetically modified thermophilic or mesophilic microorganism, wherein a first native gene is partially, substantially, or completely deleted, silenced, inactivated, or down-regulated, which first native gene encodes a first native enzyme involved in the metabolic production of an organic acid or a salt thereof, thereby increasing the native ability of said thermophilic or mesophilic microorganism to produce ethanol as a fermentation product. In certain embodiments, the aforementioned microorganism further comprises a first non-native gene, which first non- native gene encodes a first non-native enzyme involved in the metabolic production of ethanol. Another aspect of the invention relates to a process for converting lignocellulosic biomass to ethanol, comprising contacting lignocellulosic biomass with a genetically modified thermophilic or mesophilic microorganism.

L'invention concerne un micro-organisme thermophile ou mésophile génétiquement modifié, dans lequel un premier gène natif est partiellement, sensiblement, ou complètement supprimé, rendu muet, inactivé, ou diminué, ce premier gène natif codant une première enzyme native impliquée dans la production métabolique d'un acide organique ou d'un sel de celui-ci, augmentant ainsi la capacité native du micro-organisme thermophile ou mésophile à produire de l'éthanol en tant que produit de fermentation. Dans certains modes de réalisation, les micro-organismes mentionnés ci-dessus comprennent en outre un premier gène non natif, ce premier gène non natif codant une première enzyme non native impliquée dans la production métabolique de l'éthanol. Un autre aspect de l'invention concerne un procédé pour convertir la biomasse lignocellulosique en éthanol, comprenant la mise en contact de la biomasse lignocellulosique avec un micro-organisme thermophile ou mésophile génétiquement modifié.

LandOfFree

Say what you really think

Search LandOfFree.com for Canadian inventors and patents. Rate them and share your experience with other people.

Rating

Gene knockout mesophilic and thermophilic organisms, and... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Gene knockout mesophilic and thermophilic organisms, and..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Gene knockout mesophilic and thermophilic organisms, and... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFCA-PAI-O-1778895

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.