Gene regulator fusion proteins and methods of using the same...

Details Gene regulator fusion proteins and methods of using the same... Gene regulator fusion proteins and methods of using the same...

C - Chemistry, Metallurgy

12

N

C12N 15/10 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2319114

Method and gene regulator fusion proteins are disclosed utilizing a bacterial reporter system to quickly and easily identify mutations of a target protein, such as a protease, that confer resistance to a chemotherapeutic agent directed against that target protein.

L'invention concerne des procédés et des protéines de fusion régulatrices de gènes utilisant un système rapporteur bactérien pour identifier rapidement et facilement les mutations d'une protéine cible, telle qu'une protéase, mutations qui confèrent une certaine résistance à un agent chimiothérapeutique dirigé contre cette protéine cible.

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