Gene repair involving excision of targeting dna

Details Gene repair involving excision of targeting dna Gene repair involving excision of targeting dna

C - Chemistry, Metallurgy

12

N

C12N 15/90 (2006.01) C12N 9/22 (2006.01) A61K 48/00 (2006.01)

Patent

CA 2360878

Methods of modifying, repairing, attenuating and inactivating a gene or other chromosomal DNA in a cell through SCEI-induced recombination are disclosed. Also disclosed are methods of treating or prophylaxis of a genetic disease in an individual in need thereof.

L'invention concerne des méthodes permettant de modifier, de réparer, d'atténuer et d'inactiver un gène ou autre ADN chromosomique dans une cellule par recombinaison induite par SCEI. Cette invention concerne aussi des méthodes de traitement ou de prophylaxie d'une maladie génétique chez un patient le nécessitant.

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