C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/90 (2006.01) C12N 9/22 (2006.01) C12N 15/62 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2361191
Methods of modifying, repairing, attenuating and inactivating a gene or other chromosomal DNA in a cell through SceI-induced double strand break are disclosed. Also disclosed are methods of treating or prophylaxis of a genetic disease in an individual in need thereof. Further disclosed are chimeric restriction endonucleases.
L'invention concerne des procédés relatifs à la modification, la réparation, l'atténuation et l'inactivation d'un gène ou autre ADN chromosomique dans une cellule, ainsi que des procédés relatifs au traitement ou à la prévention de maladies génétiques chez un individu. L'invention concerne en outre des endonucléases de restriction chimériques.
Choulika Andre
Mulligan Richard C.
Norton Rose Or S.e.n.c.r.l.,s.r.l./llp
The Children's Medical Center Corporation
The Institute Pasteur
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