Gene replacement as a tool for the construction of...

C - Chemistry – Metallurgy – 12 – N

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195/1.22, 195/1.

C12N 1/15 (2006.01) A61K 31/135 (2006.01) A61K 31/16 (2006.01) A61K 31/19 (2006.01) C07C 69/753 (2006.01) C07H 21/04 (2006.01) C12N 1/00 (2006.01) C12N 1/14 (2006.01) C12N 15/00 (2006.01) C12N 15/09 (2006.01) C12N 15/31 (2006.01) C12N 15/56 (2006.01) C12N 15/59 (2006.01) C12N 15/63 (2006.01) C12N 15/80 (2006.01) C12N 15/90 (2006.01) C12P 19/00 (2006.01) C12P 21/00 (2006.01) C12P 21/02 (2006.01)

Patent

CA 1341226

Transformation of Aspergillus, particularly A. niger is demonstrated. Integration at the glucoamylase locus is exemplified. A chymosin expression construct is inserted at a locus, where the chymosin may be joined to a signal sequence for efficient secretion.

608154

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