Gene sequence variances with utility in determining the...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/52 (2006.01) C07H 21/00 (2006.01) C07H 21/04 (2006.01) C12N 15/12 (2006.01) C12Q 1/68 (2006.01) C07K 14/705 (2006.01) C12N 9/00 (2006.01)

Patent

CA 2335649

The present disclosure describes the use of genetic variance information for folate transport or metabolism genes or pyrimidine transport or metabolism genes in the selection of effective methods of treatment of a disease or condition. The variance information is indicative of the expected response of a patient to a method of treatment. Methods of determining relevant variance information and additional methods of using such variance information are also described.

L'invention concerne l'utilisation des informations sur la variance génétique en manière de transport de folates ou de gènes de métabolisme ou de transport de pyrimidine ou de gènes de métabolisme dans le traitement d'une maladie ou d'un état. Les informations sur la variance indiquent la réaction attendue d'un patient à un procédé de traitement déterminé. L'invention concerne également des procédés pour déterminer des informations pertinentes sur la variance et des procédés supplémentaires d'utilisation de ces informations concernant la variance.

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