Gene silencing by using micro-rna molecules

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/82 (2006.01)

Patent

CA 2541970

The invention provides methods and compositions useful in target sequence suppression and target sequence validation. The invention provides polynucleotide constructs useful gene silencing, as well as cells, plants and seeds comprising the polynucleotides. The invention also provides a method for using microRNA to silence a target sequence.

L'invention concerne des procédés et des compositions utiles dans la suppression et la validation d'une séquence cible. Cette invention concerne des constructions polynucléotidiques utiles dans le silençage génique, ainsi que des cellules, des plantes et des semences comportant lesdits polynucléotides. Cette invention concerne enfin un procédé d'utilisation de micro-ARN dans le silençage d'une séquence cible.

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