Gene silencing by using micro-rna molecules

Details Gene silencing by using micro-rna molecules Gene silencing by using micro-rna molecules

C - Chemistry, Metallurgy

12

N

C12N 15/82 (2006.01)

Patent

CA 2541914

The invention provides methods and compositions useful in target sequence suppression and target sequence validation. The invention provides polynucleotide constructs useful for gene silencing, as well as cells, plants and seeds comprising the polynucleotides. The invention also provides a method for using microRNA to silence a target sequence.

L'invention concerne des procédés et des compositions utiles pour la suppression de séquences cibles et la validation de séquences cibles. L'invention concerne en outre des constructions polynucléotidiques utiles pour l'extinction génique aussi que des cellules, des plantes et des semences comportant lesdits polynucléotides. L'invention concerne également un procédé pour l'utilisation de micro-ARN pour l'extinction d'un séquence cible.

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