Gene targeting method

Details Gene targeting method Gene targeting method

C - Chemistry, Metallurgy

12

N

C12N 15/09 (2006.01) C12N 15/90 (2006.01)

Patent

CA 2401677

The invention relates to a method of gene targeting in a transformable host organism, and compositions useful for carrying out the method. The method of gene targeting provides improvement over previous gene targeting methods since it is generally applicable over a wide variety of transformable organisms. It provides time savings in producing organisms with specific gene modifications, and it does not require a pluripotential cell line. The targeting method of the invention exploits the endogenous cellular process of homologous recombination to implement gene targeting at essentially any known gene.

L'invention concerne un procédé de ciblage génique dans un organisme hôte transformable, ainsi que des compositions qui permettent de réaliser ce procédé, lequel apporte des améliorations par rapport à des procédés de ciblage génique antérieurs, puisqu'il est généralement applicable à une grande variété d'organismes transformables. Par la production d'organismes présentant des modifications géniques spécifiques, ledit procédé permet de gagner du temps et ne requiert pas une ligne cellulaire pluripotente. Ce procédé de ciblage exploite le processus cellulaire endogène de recombinaison homologue pour mettre en oeuvre le ciblage génique sensiblement à n'importe quel gène connu.

Affiliated with

Also associated with

Rating

Gene targeting method does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Gene targeting method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Gene targeting method will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1824266