Gene therapy-1

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/53 (2006.01) A61K 31/165 (2006.01) A61K 31/167 (2006.01) A61K 38/44 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2355859

The invention hereindescribed relates to a form of cancer therapy which exploits the cytotoxic properties of acetaminophen when converted to NABQI by the metabolic activity of tumour cell specific P450; vectors for use in the delivery of P450 to tumour cells; and therapeutic compositions comprising said vectors.

L'invention ci-décrite concerne une forme de thérapie du cancer exploitant les propriétés cytotoxiques de l'acétaminophène une fois converti en NABQI par l'activité métabolique de la P450 spécifique aux cellules tumorales; des vecteurs destinés à être utilisés dans l'administration de P450 à des cellules tumorales; et des compositions thérapeutiques contenant lesdits vecteurs.

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