Gene therapy for cardiomyopathy

Details Gene therapy for cardiomyopathy Gene therapy for cardiomyopathy

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 9/127 (2006.01) A61K 35/76 (2006.01) A61K 38/18 (2006.01) A61K 38/22 (2006.01) A61P 9/04 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2354029

This invention enables the repair of cardiac function by noninvasive administration of an HGF gene in the form of Sendai virus (HVJ)-liposome into the affected cardiac muscle, thereby inducing angiogenesis of the cardiac muscle layer and repressing fibrosis.

Administration non-invasive de gène HGF sous la forme de liposome-virus de Sendai (HVJ) dans le myocarde lésé échographié, permettant de favoriser l'angiogenèse, d'inhiber la fibrose dans la couche myocardique, et de rétablir ainsi la fonction cardiaque.

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