Gene therapy for cerebrovascular disorders

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01) A61K 35/76 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2348906

Cerebrovascular disorders (cerebrovascular obstruction, cerebral infarction, cerebral thrombosis, cerebral embolism, cerebral attack, cerebral hemorrhage, Willis' circle occlusion, cerebrovascular dementia, Alzheimer's dementia, etc.) can be efficaciously treated or prevented by transferring an HGF (hepatocyte growth factor) gene and/or a VEGF (vascular endothelial growth factor) gene into the subarachnoidal space of humans.

il est possible de traiter efficacement ou de prévenir des troubles cérébro-vasculaires (l'obstruction cérébro-vasculaire, l'infarctus cérébral, la thrombose cérébrale, l'hémorragie cérébrale, l'occlusion du cercle artériel de Willis, la démence cérébro-vasculaire, la maladie d'Alzheimer, etc.) par transfert d'un gène du facteur de croissance des hépatocytes (HGF) et/ou d'un gène du facteur de croissance endothéliale (VEGF) dans l'espace sous-arachnoïdien humain.

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