C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/60 (2006.01) A61K 48/00 (2006.01) C12N 9/88 (2006.01) C12N 15/85 (2006.01) C12N 15/86 (2006.01) A61K 38/51 (2006.01)
Patent
CA 2262406
The present invention relates to methods and compositions for enhancing cardiac function in mammalian hearts by inserting transgenes that increase .beta.-adrenergic responsiveness within the myocardium. The present invention can thus be used in the treatment of heart disease, especially congestive heart failure.
Procédés et compositions permettant d'améliorer la fonction cardiaque dans des coeurs de mammifères par introduction de transgènes qui augmentent la réactivité .beta.-adrénergique dans le myocarde. Cette invention peut par conséquent être utilisée dans le traitement des maladies cardiaques et plus particulièrement de l'insuffisance cardiaque globale.
Gao Meihua
Hammond H. Kirk
Insel Paul A.
Ping Peipei
Post Steven R.
Borden Ladner Gervais Llp
The Regents Of The University Of California
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