A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 38/44 (2006.01) A61P 9/10 (2006.01) C12N 15/53 (2006.01) C12N 15/86 (2006.01)
Patent
CA 2378740
The invention relates to gene therapy for enhancing and/or inducing angiogenesis, wherein use is made of a nucleic acid sequence encoding Nitric Oxide Synthase (NOS). In particular, the nucleic acid sequence is administered in a systemic treatment, preferably comprising isolated tissue perfusion.
La présente invention se rapporte à une thérapie génique destinée au renforcement et/ou à l'induction de l'angiogenèse et consistant à utiliser une séquence d'acides nucléiques codant pour la monoxyde-d'azote synthase (NOS). L'invention se rapporte particulièrement à l'administration d'une telle séquence d'acides nucléiques au cours d'un traitement systémique comprenant, de préférence, une irrigation de tissus isolés.
Verlinden Stefan Frederik Franciscus
Vogels Ronald
Borden Ladner Gervais Llp
Crucell Holland B.v.
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