Gene therapy for obesity

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/16 (2006.01) A01K 67/027 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07K 14/575 (2006.01) C07K 14/72 (2006.01) C12N 15/85 (2006.01) C12N 15/86 (2006.01) C12Q 1/00 (2006.01)

Patent

CA 2258755

Gene therapy can treat obesity in mammals. An obesity regulating gene is delivered to a mammal. Preferably, the gene encodes letpin or a leptin receptor. The protein which is delivered and expressed in vivo is more effective than protein which is injected into the animal.

La thérapie génique peut traiter l'obésité chez les mammifères. On administre un gène de régulation de l'obésité à un mammifère. De préférence, le gène code la leptine ou un récepteur de la leptine. La protéine qui est administrée et exprimée in vivo est plus efficace que la protéine qui est injectée dans l'animal.

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