Gene therapy of pulmonary disease

Details Gene therapy of pulmonary disease Gene therapy of pulmonary disease

C - Chemistry, Metallurgy

12

N

C12N 15/24 (2006.01) A61K 35/76 (2006.01) A61K 38/20 (2006.01) A61K 45/06 (2006.01) A61K 48/00 (2006.01) A61P 29/00 (2006.01) C07K 14/54 (2006.01) C12N 15/86 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2373588

The present invention provides methods of treating pulmonary inflammatory diseases through viral IL-10 gene therapy protocols. Acute and chronic pulmonary inflammatory diseases are treated through the administration of a recombinant vector expressing viral IL-10 alone or in combination with additional therapeutic agents.

L'invention concerne des procédés relatifs au traitement des maladies pulmonaires inflammatoires par le biais de protocoles de thérapie génique à base d'IL-10 virale. On peut traiter les états aigus et chroniques de ces maladies en administrant un vecteur de recombinaison qui exprime l'IL-10 virale, seul ou en combinaison avec des agents thérapeutiques additionnels.

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