Gene therapy to promote angiogenesis and/or the treatment of...

A - Human Necessities – 61 – K

Patent

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A61K 48/00 (2006.01) A61K 38/08 (2006.01) A61P 9/00 (2006.01) C07K 7/14 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2396779

Nucleic acid delivery vehicles for enhancing and/or inducing angiogenesis are provided. The delivery vehicles comprise a nucleic acid encoding angiotensin 1- 7 or a functional part, derivative and/or analogue thereof. The vehicles are among others suited for the treatment of heart failure.

L'invention concerne des véhicules de distribution d'acide nucléique servant à renforcer et/ou à induire l'angiogenèse. Ces véhicules de distribution comprennent un acide nucléique codant pour l'angiotensine 1-7 ou une partie fonctionnelle, un dérivé et/ou un analogue de l'angiotensine 1-7. Ces véhicules conviennent notamment pour la traitement de l'insuffisance cardiaque.

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